Inhibition Activity Alpha-Glucosidase Enzyme And Toxicity From Ethanol Extract Of Caulerpa Seaweed

Caulerpa is a green macroalgae found on Lemukutan Island, West Kalimantan. contains bioactive compounds that have potential to inhibit the alpha-glucosidase enzyme for people with diabetes mellitus. Inhibition of will an impact delaying glucose absorption. In addition, it necessary carry out toxicity test detect toxic effects and assess safety in use compounds. Therefore, purpose this study was determine inhibitory activity ethanolic extract seaweed Island waters. Identification secondary metabolites determined from phytochemical tests. Inhibitory by using enzymatic reactions, while method BSLT. The showed percentage yield ethanol 3.66%. content positive alkaloids, flavonoids, saponins, tannins, steroids, phenolics. had highest inhibition concentration 300 ppm indicating percent 16.85%. Toxicity obtained LC50 value 598.19 which classified as low toxic.